|
|
S-adenosyl-L-methionine + Zymosterol <=> H+ + S-adenosyl-L-homocysteine + fecosterol
|
2.1.1.142
cycloartenol 24-C-methyltransferase
2.1.1.143
24-methylenesterol C-methyltransferase
2.1.1.41
sterol 24-C-methyltransferase
|
–
–
–
|
MK
|
|
BRENDA:
BR43897
KEGG:
R04427
MetaCyc:
RXN3O-178
SABIO-RK:
4114
|
|
|
|
Zymosterol + NADP+ <=> H+ + zymosterone + NADPH
|
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
–
–
|
BMK
|
|
BRENDA:
BS374946
KEGG:
R12405
MetaCyc:
RXN66-319
|
|
|
|
5alpha-cholesta-7,24-dien-3beta-ol <=> Zymosterol
|
5.3.3.5
cholestenol Delta-isomerase
|
–
|
BMK
|
|
BRENDA:
BS399747
KEGG:
R04804
MetaCyc:
RXN66-320
SABIO-RK:
4455
|
|
|
|
Zymosterol + NADPH <=> 5alpha-cholesta-8-en-3beta-ol + NADP+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
K
|
|
BRENDA:
BS189400
KEGG:
R07498
|
|
|
|
Cycloartenol <=> Zymosterol
|
not assigned
|
–
|
|
|
KEGG:
R03765
|
|
|
|
31-norcycloartenol <=> Zymosterol
|
5.5.1
|
–
|
M
|
|
MetaCyc:
RXN-11876
|
|
|
|
Zymosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-11881
|
|
|
|
Zymosterol + NADP+ <=> 26,27-dehydrozymosterol + NADPH + H+
|
1.3.1
|
–
|
|
|
MetaCyc:
RXN-16214
|
|
|
|
Zymosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-hydroxymethyl-14alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21165
|
|
|
|
Zymosterol + ferricytochrome_b5 + O2 + H+ <=> cholesta-5,8,24-trien-3beta-ol + ferricyctochrome_b5 + H2O
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
|
|
BRENDA:
BS434482
|
|
|
|
oleoyl-CoA + Zymosterol <=> CoA + zymosteryl_oleate
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320760
|
|
|
|
Zymosterol + S-adenosyl-L-methionine <=> 24-methylzymosta-8,25(27)-dienol + S-adenosyl-L-homocysteine
|
2.1.1.41
sterol 24-C-methyltransferase
|
–
|
|
|
BRENDA:
BS319711
|
|
|
|
S-adenosyl-L-methionine + Zymosterol <=> S-adenosyl-L-homocysteine + fecosterol + episterol + stigmasta-8,24-dienol + DELTA7-avenasterol
|
2.1.1.143
24-methylenesterol C-methyltransferase
|
–
|
|
|
BRENDA:
BS232406
|
|
|
|
zymosterone + NADH <=> Zymosterol + NAD+
|
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
|
|
|
BRENDA:
BS385979-a
|
|
|
|
Zymosterol <=> cholesta-7,24-dienol
|
5.3.3.5
cholestenol Delta-isomerase
|
–
|
|
|
BRENDA:
BS368684
|
|